Discover ANNOVERA®

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Help Her Start Her
Journey Of Contraceptive
Empowerment

Most women with commercial insurance have unrestricted access to ANNOVERA® nationwide, many without a copay

vitaCare℠ Prescription Services can simplify the experience for you and your patients

Savings

The ANNOVERA Savings Program is available to ensure patients with a copayment responsibility who have met their deductible pay as little as $60.* That’s about $5 a month for 1 full year of contraceptive protection.

Convenience

Customer Care Advocates can assist in getting ANNOVERA delivered to your patients’ local pharmacy or right to their home for no additional charge.

Support

Dedicated Pharmacists and Pharmacy Technicians provide ongoing support, including refill programs and replacement assistance if the ring is lost or damaged.

Call 1-888-228-2560 to get more details about ANNOVERA savings and support.

Download the copay card
*For eligible patients with a copayment responsibility who have met their deductible. Offer not valid for patients enrolled in Medicare, Medicaid, or other federal or state healthcare programs. Please see Program Terms, Conditions, and Eligibility Criteria. **Message and data rates may apply. Reply HELP for help; reply STOP to cancel at any time. Up to 20 messages per month per request. vitaCare Prescription Services is wholly owned and operated by TherapeuticsMD, Inc.
Visit savings.annovera.com to download the copay card

Sample Letter of Medical Necessity

For your patients not covered or in a plan with a high deductible, a letter of medical necessity can assist in securing coverage with no copayment.

To help your patients with access and reimbursement, download the Sample Letter below:

Download PDF VersionDownload letter now
Download Word VersionDownload letter now

For clinical or scientific inquiries about ANNOVERA,
please click below:

Medical Affairs

Learn more today. Call 1-888-670-9320 to speak with a sales representative.

IMPORTANT SAFETY INFORMATION

WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS

See full prescribing information for complete boxed warning.

  • Females over 35 years old who smoke should not use ANNOVERA.
  • Cigarette smoking increases the risk of serious cardiovascular events from combination hormonal contraceptive use.

CONTRAINDICATIONS

ANNOVERA (segesterone acetate and ethinyl estradiol vaginal system) is contraindicated and should not be used in women with a high risk of arterial or venous thrombotic diseases; current or history of breast cancer or other estrogen- or progestin-sensitive cancer; liver tumors, acute hepatitis, or severe (decompensated) cirrhosis; undiagnosed abnormal uterine bleeding; hypersensitivity to any of the components of ANNOVERA; and use of Hepatitis C drug combinations containing ombitasvir/paritaprevir/ritonavir, with or without dasabuvir.


WARNINGS AND PRECAUTIONS

  • Stop ANNOVERA if a thrombotic or thromboembolic event occurs, and at least 4 weeks before and through 2 weeks after major surgery. Start ANNOVERA no earlier than 4 weeks after delivery, in females who are not breastfeeding. Consider cardiovascular risk factors before initiating in all females, particularly those over 35 years.
  • Discontinue if jaundice occurs.
  • Stop ANNOVERA prior to starting therapy with the combination drug regimen ombitasvir/paritaprevir/ritonavir. ANNOVERA can be restarted 2 weeks following completion of this regimen.
  • Do not prescribe ANNOVERA for females with uncontrolled hypertension or hypertension with vascular disease. Monitor blood pressure and stop use if blood pressure rises significantly in females with well-controlled hypertension.
  • Monitor glucose in pre-diabetic or diabetic females taking ANNOVERA. Consider an alternate contraceptive method for females with uncontrolled dyslipidemias.
  • Patients using ANNOVERA who have a significant change in headaches or irregular bleeding or amenorrhea should be evaluated. ANNOVERA should be discontinued if indicated.
  • Other warnings include: gallbladder disease; depression; cervical cancer; increased serum concentrations of binding globulins; hereditary angioedema; chloasma (females who tend to develop chloasma should avoid exposure to the sun or UV radiation while using ANNOVERA); toxic shock syndrome (TSS) (if a patient exhibits symptoms of TSS, remove ANNOVERA, and initiate appropriate medical treatment); vaginal use (ANNOVERA may not be suitable for females with conditions that make the vagina more susceptible to vaginal irritation or ulceration).

ADVERSE REACTIONS

The most common adverse reactions reported in at least 5% of women who received ANNOVERA were: headache/migraine, nausea/vomiting, vulvovaginal mycotic infection/candidiasis, lower/upper abdominal pain, dysmenorrhea, vaginal discharge, urinary tract infection, breast pain/tenderness/discomfort, bleeding irregularities including metrorrhagia, diarrhea, and genital pruritus.


DRUG INTERACTIONS

Drugs or herbal products that induce certain enzymes, including CYP3A4, may decrease the effectiveness of ANNOVERA or increase breakthrough bleeding. Counsel patients to use a back-up or alternative method of contraception when enzyme inducers are used with ANNOVERA.



INDICATION

ANNOVERA is a progestin/estrogen combination hormonal contraceptive indicated for use by females of reproductive potential to prevent pregnancy.


Limitations of Use: ANNOVERA has not been adequately studied in females with a body mass index >29 kg/m2.



Please note that this information is not comprehensive. Please click here for the Full Prescribing Information, including BOXED WARNING.



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