Inserted for 21 continuous days and removed 7 days for 13 cycles
Learn Why Patients
Proven patient satisfaction1–
~90% of women in a clinical trial were satisfied with ANNOVERA as a form of contraception, the majority of whom had no prior experience with vaginal rings.*
Women rated ANNOVERA highly for:1
- Ease of use
- Comfort while inserted
- Experience during sexual activity
- Low rate of expulsions†
*In an ANNOVERA Phase 3 study, a product acceptability questionnaire was administered and completed at the end of Cycle 3 (n=1036). Results based on data from 905 subjects in the areas of ease-of-use, expulsion, side effects, and sex/intercourse.
†In clinical trials with 2308 women, the rate of expulsion was 25%. Expulsion occurred primarily in the first few weeks as women were getting used to the product, and resulted in 1.4% discontinuation.
HER in mind
- Fertility and menstruation control for a full year‡
- Soft and flexible for easy insertion and removal
- No wider than a tampon during insertion2
‡Inserted for 21 continuous days and removed 7 days for 13 cycles.
Composed of a soft, pliable, silicone elastomer, ANNOVERA’s shape, size, and texture were designed for easy insertion
and comfortable use.
Is ANNOVERA Right
For Your Patients?
With just one prescription, ANNOVERA puts HER in control for a full year‡ and may be appropriate for women who:
- Want a long-term option with no procedure
- Are between pregnancies – don’t want the lack of flexibility of an IUD, and tired of a daily pill
- Are always on the go and want annual birth control without monthly refills
- Are not interested in future pregnancies and want long-lasting contraception that they control
Successfully starting patients on ANNOVERA3
Women who have not used a hormonal contraceptive in the preceding cycle or after copper IUD removal
- Insert ANNOVERA between days 2 and 5 of their regular menstrual bleeding; no back-up contraception is needed
- If menstrual cycles are irregular or if the start is more than 5 days from the last menstrual bleeding, women should use an additional barrier method for the first 7 days of ANNOVERA use
Women using a combination hormonal contraceptive (CHC)
- Women who are not pregnant and are consistently and correctly using a CHC can successfully switch to ANNOVERA on any day of the CHC cycle (Day 1-28) without back-up contraception as long as no more than 7 hormone-free days occur before starting ANNOVERA
Women using a progestin-only contraceptive
- Women who remain on schedule with their current birth control and have no contraindication to ethinyl estradiol can successfully switch to ANNOVERA from:
Pills: at the time of their next pill
Injection: at the time of their next scheduled injection
Implant or an IUD: at the time of their implant or IUS removal
- After switching from a progestin-only method, an
additional barrier method should be used for initial 7
days of ANNOVERA use
- Merkatz RB, Plagianos M, Hoskin E, et al. Acceptability of the Nestorone®/ ethinyl estradiol contraceptive vaginal ring: development of a model; implications for introduction. Contraception. 2014;90(5):514–521. doi:10.1016/j.contraception.2014.05.015.
- Carlin EP, Spielmann HM, inventors; The Proctor & Gamble Company, assignee. Tampon. US Patent 7,338,483 B2. March 4, 2008.
- Annovera® [Full Prescribing Information]. Raleigh , NC: Mayne Pharma, Inc; 2022.